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Depression and smoking: A 5-year prospective study of patients with major depressive disorder

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dc.contributor.authorHolma, Irina
dc.contributor.authorHolma, Mikael
dc.contributor.authorMelartin, Tarja
dc.contributor.authorIsometsä, Erkki
dc.contributor.authorKetokivi, Mikko
dc.contributor.rorhttps://ror.org/02jjdwm75
dc.date.accessioned2024-07-08T13:14:56Z
dc.date.available2024-07-08T13:14:56Z
dc.date.issued2013
dc.description.abstractBackground Major depressive disorder (MDD) and smoking are major public health problems and epidemiologically strongly associated. However,the relationship between smoking and depression and whether this is influenced by common confounding factors remain unclear,in part due to limited longitudinal data on covariation. Methods In the Vantaa Depression Study,psychiatric out- and inpatients with DSM-IV MDD and aged 20-59 years at were followed from baseline to 6 months,18 months,and 5 years. We investigated course of depression,smoking,and comorbid alcohol-use disorders among the 214 patients (79.6% of 269) participating at least three time points; differences between smoking versus nonsmoking patients,and covariation of MDD,smoking,and alcohol-use disorders. Results Overall,31.3% of the patients smoked regularly,41.1% intermittently,and 27.6% never. Smokers were younger,had more alcohol-use disorders and Cluster B and C personality disorder symptoms,a higher frequency of lifetime suicide attempts,higher neuroticism,smaller social networks,and lower perceived social support than never smokers. Smoking and depression had limited longitudinal covariation. Depression,smoking,and alcohol-use disorders all exhibited strong autoregressive tendencies. Conclusions Among adult psychiatric MDD patients,smoking is strongly associated with substance-use and personality disorders,which may confound research on the impact of smoking. Rather than depression or smoking covarying or predicting each other,depression,smoking,and alcohol-use disorders each have strong autoregressive tendencies. These findings are more consistent with common factors causing their association than either of the conditions strongly predisposing to the other. © 2013 Wiley Periodicals,Inc.
dc.description.keywordalcoholism
dc.description.keywordmajor depressive disorder
dc.description.keywordpersonality disorders
dc.description.keywordtobacco smoking
dc.formatapplication/pdf
dc.identifier.citationHolma, I. A., Holma, K. M., Melartin, T. K., Ketokivi, M., & Isometsä, E. T. (2013). Depression and smoking: A 5?year prospective study of patients with major depressive disorder. Depression and Anxiety, 30(6), 580-588.
dc.identifier.doihttps://doi.org/10.1002/da.22108
dc.identifier.issn10914269
dc.identifier.officialurlhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-84878750979&doi=10.1002%2fda.22108&partnerID=40&md5=e017fa389105e9f31a57579c99d6bbe1
dc.identifier.urihttps://hdl.handle.net/20.500.14417/3102
dc.issue.number6
dc.journal.titleDepression and Anxiety
dc.language.isoeng
dc.page.final588
dc.page.initial580
dc.page.total7
dc.relation.departmentOperations & Technology
dc.relation.entityIE University
dc.relation.schoolIE Business School
dc.rightsAttribution-NonCommercial 4.0 International
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0/
dc.subjectalcoholism; major depressive disorder; personality disorders; tobacco smoking
dc.subject.keywordalcoholism
dc.subject.keywordmajor depressive disorder
dc.subject.keywordpersonality disorders
dc.subject.keywordtobacco smoking
dc.subject.otheralcohol
dc.subject.otheradult
dc.subject.otheralcohol abuse
dc.subject.otheralcohol consumption
dc.subject.otherarticle
dc.subject.othercomorbidity
dc.subject.othercontrolled study
dc.subject.otherDSM-IV
dc.subject.otherfemale
dc.subject.otherfollow up
dc.subject.otherhuman
dc.subject.othermajor clinical study
dc.subject.othermajor depression
dc.subject.othermale
dc.subject.othermental patient
dc.subject.otherneurosis
dc.subject.otherpersonality disorder
dc.subject.otherpriority journal
dc.subject.otherprospective study
dc.subject.othersmoking
dc.subject.othersmoking habit
dc.subject.othersocial network
dc.subject.othersocial support
dc.subject.othersuicide attempt
dc.subject.otherAdult
dc.subject.otherAlcoholism
dc.subject.otherComorbidity
dc.subject.otherDepressive Disorder
dc.subject.otherMajor
dc.subject.otherFemale
dc.subject.otherFinland
dc.subject.otherHealth Surveys
dc.subject.otherHumans
dc.subject.otherMale
dc.subject.otherMiddle Aged
dc.subject.otherPersonality Disorders
dc.subject.otherProspective Studies
dc.subject.otherSmoking
dc.subject.otherSocial Support
dc.subject.otherSuicide
dc.subject.otherAttempted
dc.titleDepression and smoking: A 5-year prospective study of patients with major depressive disorder
dc.typeinfo:eu-repo/semantics/article
dc.version.typeinfo:eu-repo/semantics/publishedVersion
dc.volume.number30
dspace.entity.typePublication
person.identifier.scopus-author-id23990797700
person.identifier.scopus-author-id23990868900
person.identifier.scopus-author-id6602968779
person.identifier.scopus-author-id6506337576
person.identifier.scopus-author-id35233236400
relation.isAuthorOfPublication713175cc-b5d4-44f0-bf3f-bd1faa9a9d05
relation.isAuthorOfPublication.latestForDiscovery713175cc-b5d4-44f0-bf3f-bd1faa9a9d05
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